Scientific work

Prof. Dr. Safa Barış

395 publications. The source of the information is stated next to each publication.

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  1. Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency

    Journal of Allergy and Clinical Immunology, 2024

    DOI 10.1016/j.jaci.2023.12.020 PMID 38185418 20 citations (OpenAlex) Open-access full textSource: OpenAlex

  2. Insights into Patient Experiences with Facilitated Subcutaneous Immunoglobulin Therapy in Primary Immune Deficiency: A Prospective Observational Cohort

    Journal of Clinical Immunology, 2024

    DOI 10.1007/s10875-024-01771-0 PMID 39098942 11 citations (OpenAlex) Open-access full textSource: OpenAlex

  3. Delineating the Clinical and Immunologic Characteristics: A Comparative Study of Inborn Errors of Immunity in Adult versus Pediatric Diagnosed

    International Archives of Allergy and Immunology, 2024

    DOI 10.1159/000540538 PMID 39226882 10 citations (OpenAlex) Open-access full textSource: OpenAlex

  4. Ruxolitinib treatment ameliorates clinical, immunologic, and transcriptomic aberrations in patients with STAT3 gain-of-function disease

    Journal of Allergy and Clinical Immunology, 2024

    DOI 10.1016/j.jaci.2024.11.032 PMID 39631446 9 citations (OpenAlex) Open-access full textSource: OpenAlex

  5. TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome

    Nature Communications, 2024

    DOI 10.1038/s41467-024-45948-y PMID 37720017 9 citations (OpenAlex) Open-access full textSource: OpenAlex

  6. Diverse Clinical and Immunological Profiles in Patients with IPEX Syndrome: a Multicenter Analysis from Turkey

    Journal of Clinical Immunology, 2024

    DOI 10.1007/s10875-024-01791-w PMID 39283523 8 citations (OpenAlex) Open-access full textSource: OpenAlex

  7. DOCK8 deficiency due to a deep intronic variant in two kindreds with hyper-IgE syndrome

    Clinical Immunology, 2024

    DOI 10.1016/j.clim.2024.110384 PMID 39437980 2 citations (OpenAlex) Open-access full textSource: OpenAlex

  8. Identification of a Novel Primary Atopic Disorder due to STAT6 Gain-of-Function Mutations

    Turkish Journal of Immunology, 2024

    DOI 10.4274/tji.galenos.2023.39200 3 citations (OpenAlex) Open-access full textSource: OpenAlex

  9. Structure and Function of the LRBA Protein

    Turkish Journal of Immunology, 2024

    DOI 10.4274/tji.galenos.2023.21939 2 citations (OpenAlex) Open-access full textSource: OpenAlex

  10. Tracing the Spectrum of Inborn Errors of Immunity from Past to Present

    Turkish Journal of Immunology, 2024

    DOI 10.4274/tji.galenos.2024.00001 Open-access full textSource: OpenAlex

  11. Expanding the clinical and immunological phenotypes of PAX1-deficient SCID and CID patients

    Clinical Immunology, 2023

    DOI 10.1016/j.clim.2023.109757 PMID 37689091 10 citations (Europe PMC) Open-access full textSource: ORCID

  12. Therapeutic modalities and clinical outcomes in a large cohort with LRBA deficiency and CTLA4 insufficiency

    Journal of Allergy and Clinical Immunology, 2023

    DOI 10.1016/j.jaci.2023.08.004 PMID 37595759 61 citations (OpenAlex) Open-access full textSource: OpenAlex

  13. Defective Treg generation and increased type 3 immune response in leukocyte adhesion deficiency 1

    Clinical Immunology, 2023

    DOI 10.1016/j.clim.2023.109691 PMID 37433423 8 citations (OpenAlex) Open-access full textSource: OpenAlex

  14. Intrafamilial clinical variability of CTLA-4 insufficiency hindering early diagnosis

    Klinische Pädiatrie, 2023

    DOI 10.1055/a-2175-7957 PMID 37989213 Source: OpenAlex

  15. Human carmil2 deficiency underlies a broader immunological and clinical phenotype than cd28 deficiency

    Journal of Experimental Medicine, 2023

    DOI 10.1084/jem.20220275 PMID 36515678 34 citations (Europe PMC) Open-access full textSource: ORCID

  16. 25 A phase 2/3 study evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy (CHAPLE disease)

    Immunobiology, 2023

    DOI 10.1016/j.imbio.2023.152482 3 citations (OpenAlex) Open-access full textSource: OpenAlex

  17. Clinical and immunological outcomes of SARS-CoV-2 infection in patients with inborn errors of immunity receiving different brands and doses of COVID-19 vaccines

    Tuberk Toraks, 2023

    DOI 10.5578/tt.20239705 PMID 37740627 3 citations (Europe PMC) Open-access full textSource: ORCID

  18. Atypical Localization of Eczema Discriminates DOCK8 or STAT3 Deficiencies from Atopic Dermatitis

    Journal of clinical immunology, 2023

    DOI 10.1007/s10875-023-01554-z PMID 37507632 7 citations (Europe PMC) Open-access full textSource: Europe PMC

  19. Outcomes of hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome

    Blood, 2023

    DOI 10.1182/blood.2022019117 PMID 37478401 35 citations (Europe PMC) Open-access full textSource: Europe PMC

  20. Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis

    Blood, 2023

    DOI 10.1182/blood.2022018303 PMID 37249233 15 citations (Europe PMC) Open-access full textSource: Europe PMC

  21. Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity

    Journal of Allergy and Clinical Immunology, 2023

    DOI 10.1016/j.jaci.2023.06.015 PMID 37390899 78 citations (OpenAlex) Open-access full textSource: OpenAlex

  22. Severe allergic dysregulation due to a gain of function mutation in the transcription factor STAT6

    Journal of Allergy and Clinical Immunology, 2023

    DOI 10.1016/j.jaci.2023.01.023 PMID 36758835 69 citations (OpenAlex) Open-access full textSource: OpenAlex

  23. Dominant-negative heterozygous mutations in AIRE confer diverse autoimmune phenotypes

    iScience, 2023

    DOI 10.1016/j.isci.2023.106818 PMID 37235056 41 citations (OpenAlex) Open-access full textSource: OpenAlex

  24. A Rare Immunodeficiency As a Cause of Inflammatory Bowel Disease; ARPC1B Deficiency

    Clinical Immunology, 2023

    DOI 10.1016/j.clim.2023.109587 Source: OpenAlex

  25. TNFRSF13B VARIANTS ACT AS MODIFIERS TO CLINICAL PHENOTYPES IN COMMON VARIABLE IMMUNE DEFICIENCY DISORDERS

    Sağlık Bilimlerinde İleri Araştırmalar Dergisi / Journal of Advanced Research in Health Sciences, 2023

    DOI 10.26650/jarhs2023-1346155 Open-access full textSource: OpenAlex

  26. Clinical and Laboratory Factors Affecting the Prognosis of Severe Combined Immunodeficiency

    Journal of Clinical Immunology, 2022

    DOI 10.1007/s10875-022-01262-0 PMID 35451701 10 citations (Europe PMC) Open-access full textSource: OpenAlex

  27. The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2–associated multisystem inflammatory syndrome in children

    Journal of Clinical Investigation, 2022

    DOI 10.1172/jci163235 PMID 35441180 35 citations (OpenAlex) Open-access full textSource: OpenAlex

  28. Comparing the levels of CTLA-4-dependent biological defects in patients with LRBA deficiency and CTLA-4 insufficiency

    Allergy, 2022

    DOI 10.1111/all.15331 PMID 35491430 26 citations (Europe PMC) Open-access full textSource: Europe PMC

  29. Expanding the Clinical and Immunological Phenotypes and Natural History of MALT1 Deficiency

    Journal of Clinical Immunology, 2022

    DOI 10.1007/s10875-021-01191-4 PMID 35079916 35 citations (OpenAlex) Open-access full textSource: OpenAlex

  30. Adverse COVID‐19 outcomes in immune deficiencies: Inequality exists between subclasses

    Allergy, 2022

    DOI 10.1111/all.15025 PMID 34314546 32 citations (Europe PMC) Open-access full textSource: ORCID

  31. Evolution and long-term outcomes of combined immunodeficiency due to CARMIL2 deficiency

    Allergy: European Journal of Allergy and Clinical Immunology, 2022

    DOI 10.1111/all.15010 PMID 34287962 43 citations (Europe PMC) Open-access full textSource: ORCID

  32. Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry

    Clinical Immunology, 2022

    DOI 10.1016/j.clim.2022.109131 PMID 36179983 19 citations (OpenAlex) Open-access full textSource: OpenAlex

  33. A boy with a novel homozygous ZAP70 mutation presenting with a dermatological phenotype and postnatal decrease in CD8<sup>+</sup> T cells

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2022

    DOI 10.1111/pai.13756 PMID 35338726 3 citations (Europe PMC) Open-access full textSource: Europe PMC

  34. A Stk4-Foxp3-NF-κB p65 transcriptional complex promotes Treg cell activation and homeostasis

    Science immunology, 2022

    DOI 10.1126/sciimmunol.abl8357 PMID 36149942 25 citations (Europe PMC) Open-access full textSource: Europe PMC

  35. Mucus sialylation determines intestinal host-commensal homeostasis

    Cell, 2022

    DOI 10.1016/j.cell.2022.02.013 PMID 35303419 241 citations (OpenAlex) Open-access full textSource: OpenAlex

  36. Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

    Journal of Allergy and Clinical Immunology, 2022

    DOI 10.1016/j.jaci.2022.09.002 PMID 36228738 136 citations (OpenAlex) Open-access full textSource: OpenAlex

  37. The Middle East and North Africa Diagnosis and Management Guidelines for Inborn Errors of Immunity

    The Journal of Allergy and Clinical Immunology In Practice, 2022

    DOI 10.1016/j.jaip.2022.10.003 PMID 36265766 63 citations (OpenAlex) Open-access full textSource: OpenAlex

  38. Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency

    Journal of Clinical Immunology, 2022

    DOI 10.1007/s10875-021-01176-3 PMID 35028801 11 citations (OpenAlex) Open-access full textSource: OpenAlex

  39. Increased radiosensitivity and impaired DNA repair in patients with STAT3-LOF and ZNF341 deficiency, potentially contributing to malignant transformations

    Clinical & Experimental Immunology, 2022

    DOI 10.1093/cei/uxac041 PMID 35511492 8 citations (OpenAlex) Open-access full textSource: OpenAlex

  40. Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease

    Nature Immunology, 2021

    DOI 10.1038/s41590-020-00830-z PMID 33398182 41 citations (Europe PMC) Open-access full textSource: OpenAlex

  41. Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease

    Nature Immunology, 2021

    DOI 10.1038/s41590-021-01093-y PMID 34937930 17 citations (Europe PMC) Open-access full textSource: OpenAlex

  42. Mesenchymal Stem Cells Derived from Human Dental Follicle Modulate the Aberrant Immune Response in Atopic Dermatitis

    Immunotherapy, 2021

    DOI 10.2217/imt-2020-0257 PMID 33955241 9 citations (Europe PMC) Source: OpenAlex

  43. Determining T and B Cell development by TREC/KREC analysis in primary immunodeficiency patients and healthy controls

    Scandinavian Journal of Immunology, 2021

    DOI 10.1111/sji.13130 PMID 34951041 6 citations (Europe PMC) Source: OpenAlex

  44. Consensus Middle East and North Africa Registry on Inborn Errors of Immunity

    Journal of Clinical Immunology, 2021

    DOI 10.1007/s10875-021-01053-z PMID 34052995 70 citations (Europe PMC) Open-access full textSource: OpenAlex

  45. Immune dysfunction in inborn errors of immunity causing malignancies

    Expert Review of Clinical Immunology, 2021

    DOI 10.1080/1744666x.2021.1925542 PMID 33945379 6 citations (Europe PMC) Open-access full textSource: ORCID

  46. Primary Immune Regulatory Disorders and Targeted Therapies

    Turkish Journal of Hematology, 2021

    DOI 10.4274/tjh.galenos.2021.2020.0724 PMID 33442967 9 citations (Europe PMC) Open-access full textSource: ORCID

  47. Impaired respiratory burst contributes to infections in PKCδ-deficient patients

    Journal of Experimental Medicine, 2021

    DOI 10.1084/jem.20210501 PMID 34264265 33 citations (Europe PMC) Open-access full textSource: ORCID

  48. Lymphopenia with Low T and NK Cells in a Patient with USB1 Mutation, Rare Findings in Clericuzio-Type Poikiloderma with Neutropenia

    Journal of Clinical Immunology, 2021

    DOI 10.1007/s10875-021-00998-5 PMID 33624217 2 citations (Europe PMC) Source: ORCID

  49. GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension

    Journal of Experimental Medicine, 2021

    DOI 10.1084/jem.20201745 PMID 33956074 30 citations (Europe PMC) Open-access full textSource: ORCID

  50. Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations

    Nature Immunology, 2021

    DOI 10.1038/s41590-021-00910-8 PMID 33833438 64 citations (Europe PMC) Open-access full textSource: ORCID