Scientific work

Prof. Dr. Mert Erkan

148 publications. The source of the information is stated next to each publication.

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  1. Characterization of Pancreatic Stellate Cells in Pancreatic Ductal Adenocarcinoma and Cases of Chronic Pancreatitis of Various Etiologies

    Pancreatology, 2017

    DOI 10.1016/j.pan.2017.05.064 Source: OpenAlex

  2. Contemporary strategies to improve the outcome in locally advanced pancreatic cancer

    Minerva Surgery, 2017

    DOI 10.23736/s0026-4733.17.07410-7 PMID 28565894 Source: OpenAlex

  3. Preoperative biliary drainage in malignant jaundice causes a shift of the biliary microbiome and aggravates antibiotic resistance

    Pancreatology, 2016

    DOI 10.1016/j.pan.2016.05.322 Source: OpenAlex

  4. Preoperative biliary drainage in malignant jaundice causes a shift of the biliary microbiome and aggravates antibiotic resistance

    HPB, 2016

    DOI 10.1016/j.hpb.2016.02.181 Source: OpenAlex

  5. Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver

    Gastroenterology, 2016

    DOI 10.1053/j.gastro.2016.07.043 PMID 27506299 115 citations (Europe PMC) Source: OpenAlex

  6. Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer

    Clinical Cancer Research, 2016

    DOI 10.1158/1078-0432.ccr-15-2432 PMID 27663591 66 citations (Europe PMC) Open-access full textSource: OpenAlex

  7. Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

    Gut, 2016

    DOI 10.1136/gutjnl-2015-310913 PMID 27646934 44 citations (Europe PMC) Open-access full textSource: OpenAlex

  8. Periostin and tumor-stroma interactions in non-small cell lung cancer

    Oncology Letters, 2016

    DOI 10.3892/ol.2016.5132 PMID 27895734 17 citations (Europe PMC) Open-access full textSource: OpenAlex

  9. Activated leukocyte cell adhesion molecule regulates the interaction between pancreatic cancer cells and stellate cells

    Molecular Medicine Reports, 2016

    DOI 10.3892/mmr.2016.5681 PMID 27573419 6 citations (Europe PMC) Open-access full textSource: OpenAlex

  10. Obstructive pancreatitis is a stronger fibrogenic stimulus than cancer-specific stellate cell activation in pancreatic ductal adenocarcinoma

    Pancreatology, 2016

    DOI 10.1016/j.pan.2016.05.123 Source: OpenAlex

  11. Oncogenic Kras promotes early pancreatic carcinogenesis by perpetuating elements of natural inflammatory response

    Pancreatology, 2016

    DOI 10.1016/j.pan.2015.12.041 Source: OpenAlex

  12. p53-mtor axis is a potential pathway leading to the development of pancreatic acinar cell carcinoma

    HPB, 2016

    DOI 10.1016/j.hpb.2016.01.484 Source: OpenAlex

  13. High Periostin Expression is an Independent Positive Prognostic Factor in Pancreatic Ductal Adenocarcinoma

    HPB, 2016

    DOI 10.1016/j.hpb.2016.01.275 Source: OpenAlex

  14. ER stress compromises VEGFA secretion of pancreatic cancer cells under hypoxic conditions, thereby contributing to tumor hypoxia

    HPB, 2016

    DOI 10.1016/j.hpb.2016.01.431 Source: OpenAlex

  15. Histological and molecular landscape of early pancreatic carcinogenesis

    Pancreatology, 2016

    DOI 10.1016/j.pan.2016.05.113 Source: OpenAlex

  16. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

    Nature Medicine, 2015

    DOI 10.1038/nm.3952 PMID 26390243 349 citations (Europe PMC) Open-access full textSource: OpenAlex

  17. Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms

    Clinical Cancer Research, 2015

    DOI 10.1158/1078-0432.ccr-14-1399 PMID 25717063 192 citations (Europe PMC) Source: OpenAlex

  18. The role of hypoxia in pancreatic cancer: a potential therapeutic target?

    Expert Review of Gastroenterology & Hepatology, 2015

    DOI 10.1586/17474124.2016.1117386 PMID 26560854 120 citations (Europe PMC) Source: OpenAlex

  19. Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment

    Gut, 2015

    DOI 10.1136/gutjnl-2014-308935 PMID 25841238 117 citations (Europe PMC) Open-access full textSource: OpenAlex

  20. A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling

    Gut, 2015

    DOI 10.1136/gutjnl-2014-307616 PMID 25601637 66 citations (Europe PMC) Source: OpenAlex

  21. Resectability After First-Line FOLFIRINOX in Initially Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Experience

    Annals of Surgical Oncology, 2015

    DOI 10.1245/s10434-015-4851-2 PMID 26350368 68 citations (Europe PMC) Source: OpenAlex

  22. Kif20a inhibition reduces migration and invasion of pancreatic cancer cells

    Journal of Surgical Research, 2015

    DOI 10.1016/j.jss.2015.03.070 PMID 25953216 52 citations (Europe PMC) Source: OpenAlex

  23. Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

    Oncotarget, 2015

    DOI 10.18632/oncotarget.5168 PMID 26452217 35 citations (Europe PMC) Open-access full textSource: OpenAlex

  24. Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells

    Tissue Barriers, 2015

    DOI 10.1080/21688370.2015.1037948 PMID 26451343 10 citations (Europe PMC) Open-access full textSource: OpenAlex

  25. Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

    American Journal Of Pathology, 2015

    DOI 10.1016/j.ajpath.2015.09.022 PMID 26632158 26 citations (Europe PMC) Source: OpenAlex

  26. Umbilical Microflora, Antiseptic Skin Preparation, and Surgical Site Infection in Abdominal Surgery

    Surgical Infections, 2015

    DOI 10.1089/sur.2014.163 PMID 26114397 15 citations (Europe PMC) Source: OpenAlex

  27. A common genetic variation of melanoma inhibitory activity-2 labels a subtype of pancreatic adenocarcinoma with high endoplasmic reticulum stress levels

    Scientific Reports, 2015

    DOI 10.1038/srep08109 PMID 25657029 19 citations (Europe PMC) Open-access full textSource: OpenAlex

  28. Surgery for Cystic Pancreatic Lesions in the Post-Sendai Era: A Single Institution Experience

    HPB Surgery, 2015

    DOI 10.1155/2015/847837 PMID 25873753 12 citations (Europe PMC) Open-access full textSource: OpenAlex

  29. Volumetric gain of the human pancreas after left partial pancreatic resection: A CT-scan based retrospective study

    Pancreatology, 2015

    DOI 10.1016/j.pan.2015.06.007 PMID 26145835 12 citations (Europe PMC) Source: OpenAlex

  30. Outcomes of resections for pancreatic adenocarcinoma with suspected venous involvement: a single center experience

    BMC Surgery, 2015

    DOI 10.1186/s12893-015-0086-1 PMID 26296752 8 citations (Europe PMC) Open-access full textSource: OpenAlex

  31. Strategies to improve the outcome in locally advanced pancreatic cancer.

    PubMed, 2015

    PMID 25658301 6 citations (Europe PMC) Source: OpenAlex

  32. Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma

    Molecular Cancer, 2015

    DOI 10.1186/s12943-015-0483-1 PMID 26683340 9 citations (Europe PMC) Open-access full textSource: OpenAlex

  33. Mesenchymal Wt1 positive stellate cells represent a minor source of the fibrotic response in pancreatitis

    Pancreatology, 2015

    DOI 10.1016/j.pan.2015.05.047 Source: OpenAlex

  34. Periostin promotes pancreatic carcinogenesis and metastatic spread

    Pancreatology, 2015

    DOI 10.1016/j.pan.2015.05.145 Source: OpenAlex

  35. Pankreas Tümörlerinde Laparoskopik Tedavi

    Turkiye Klinikleri General Surgery - Special Topics, 2015

    Source: OpenAlex

  36. Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment

    Zeitschrift für Gastroenterologie, 2015

    DOI 10.1055/s-0035-1559005 Source: OpenAlex

  37. Abstract B08: The role of periostin in pancreatic carcinogenesis and metastatic spread

    Cancer Research, 2015

    DOI 10.1158/1538-7445.panca2014-b08 Source: OpenAlex

  38. Intracellular autofluorescence: a biomarker for epithelial cancer stem cells

    Nature Methods, 2014

    DOI 10.1038/nmeth.3112 PMID 25262208 174 citations (Europe PMC) Source: OpenAlex

  39. Impaired Autophagy Induces Chronic Atrophic Pancreatitis in Mice via Sex- and Nutrition-Dependent Processes

    Gastroenterology, 2014

    DOI 10.1053/j.gastro.2014.12.003 PMID 25497209 149 citations (Europe PMC) Source: OpenAlex

  40. Chloroquine Targets Pancreatic Cancer Stem Cells via Inhibition of CXCR4 and Hedgehog Signaling

    Molecular Cancer Therapeutics, 2014

    DOI 10.1158/1535-7163.mct-13-0948 PMID 24785258 121 citations (Europe PMC) Source: OpenAlex

  41. The Role of Inflammation in Pancreatic Cancer

    Advances in experimental medicine and biology, 2014

    DOI 10.1007/978-3-0348-0837-8_6 PMID 24818722 86 citations (Europe PMC) Source: OpenAlex

  42. Multicenter Double-Blinded Randomized Controlled Trial of Standard Abdominal Wound Edge Protection With Surgical Dressings Versus Coverage With a Sterile Circular Polyethylene Drape for Prevention of Surgical Site Infections

    Annals of Surgery, 2014

    DOI 10.1097/sla.0000000000000954 PMID 25379844 67 citations (Europe PMC) Source: OpenAlex

  43. Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma

    Cancer Letters, 2014

    DOI 10.1016/j.canlet.2014.10.020 PMID 25449434 69 citations (Europe PMC) Source: OpenAlex

  44. Effect of gemcitabine and retinoic acid loaded PAMAM dendrimer-coated magnetic nanoparticles on pancreatic cancer and stellate cell lines

    Biomedicine & Pharmacotherapy, 2014

    DOI 10.1016/j.biopha.2014.07.003 PMID 25108345 33 citations (Europe PMC) Source: OpenAlex

  45. Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice

    Journal of Clinical Investigation, 2013

    DOI 10.1172/jci64498 PMID 23563314 109 citations (Europe PMC) Open-access full textSource: OpenAlex

  46. Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels

    Frontiers in Physiology, 2013

    DOI 10.3389/fphys.2013.00246 PMID 24062691 58 citations (Europe PMC) Open-access full textSource: OpenAlex

  47. Comparative analysis of the revenues of pylorus-preserving pancreatic head resections and laparoscopic cholecystectomies as prototypic surgical procedures in the German health-care system

    Langenbeck s Archives of Surgery, 2013

    DOI 10.1007/s00423-013-1091-4 PMID 23778973 1 citation (Europe PMC) Source: OpenAlex

  48. The Role of Non-cancerous Cells in Cancer: Pancreatic Ductal Adenocarcinoma as a Model to Understand the Impact of Tumor Microenvironment on Epithelial Carcinogenesis

    Springer eBooks, 2013

    DOI 10.1007/978-1-4614-7876-8_12 Source: OpenAlex

  49. Analysis of the extracellular matrix protein periostin in early pancreatic carcinogenesis

    Pancreatology, 2013

    DOI 10.1016/j.pan.2013.04.043 Source: OpenAlex

  50. A common variant of MIA2 and the HNF1A-MIA2-ERN1 axis reciprocally determine response to endoplasmic reticulum- and genotoxic stress in pancreatic cancer

    Pancreatology, 2013

    DOI 10.1016/j.pan.2012.12.212 Source: OpenAlex