Scientific work

Prof. Dr. Hakan Erdem

364 publications. The source of the information is stated next to each publication.

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  1. Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler

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  2. Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities) 1.Dinc A, Karaayvaz M, Calıskaner AZ, Pay S, Erdem H, Turan M. Dermographism and Atopy in Patients with Behçet’s Disease. Journal of Allergology and Clinical Immunology 10:368-371, 2000.

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  3. 2.Cömert B, Mas MR, Erdem H, Dinc A, Saglamkaya U, Cigerim M, Kuzhan O, Unal T, Kocabalkan F. Insulin Resistance in Non-Alcholic Steatohepatitis. Digest Liver Dis. 33, 253-358i 2001.

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  4. 3.Pay S, Erdem H, Serdar H, Dinc A, Simsek I, Turan M. Comparison of Synovial MMP-1 and TIMP-1 Levels in Patients with Various Inflammatory Arthritides: Is There Any Difference Between Rheumatoid Arthritis, Behçet’s Disease and Familial Mediterranean Fever? Clinical Rheumatology 21:511-515, 2002.

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  5. 4.Erdem H, Pay S, Serdar M, Simsek I, Dinc A, Musabak U, Pekel A, Turan M. Different ELR(+) angiogenic CXC chemokine profiles in synovial fluid of patients with Behçet’s disease, familial Mediterranean fever, rheumatoid arthritis, and osteoarthritis. Rheumatol Int. 2005 Dec;26(2):162-7.

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  6. 5.Tunca M, Akar S, Onen F, Ozdogan H, Kasapcopur O, Yalcinkaya F, Tutar E, Ozen S, Topaloglu R, Yilmaz E, Arici M, Bakkaloglu A, Besbas N, Akpolat T, Dinc A, Erken E, Tirpan K, Ozer HTE, Birlik M, Soyturk M, Senturk T, Balci B, Ozguc M, Dundar M, Akar E, Akar N, Ozel D, Gonen S, Misirlioglu M, Soylemezoglu O, Gunesacar R, Altiok O, Booth DR, Hawkins PN, Touitou I, Aksentijevich I, Matzner Y, Arslan S, Balaban Y, Batman F, Bayraktar Y, Apras S, Calguneri M, Duzova A, Kav T, Ozaltin F, Simsek H, Sivri B, Tatar G, Akkoc N, Kavukcu S, Soylu A, Turkmen M, Unsal E, Arisoy N, Caliskan S, Gogus F, Masatlioglu S, Sever L, Akkok N, Cakar N, Kara N, Kocak H, Ozalp S, Bilge I, Emre S, Gul A, Kamali S, Sadikoglu B, Selcukbiricik F, Sirin A, Sucu A, Bek K, Bulbul M, Delibas A, Demircin G, Erdogan O, Oner A, Ekim M, Ozkaya N, Tekin M, Demirkaya E, Erdem H, Gok F, Pay S, Islek I, Kabasakal Y, Keser G, Ozmen M, Akoglu E, Atagunduz P, Direskeneli H, Temel M, Tuglular S, Buyan N, Bakkaloglu S, Derici U,

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  7. 6.Pay S, Musabak U, Erdem H, Simsek I, Pekel A, Sengul A, Dinc A. Chimerical anti-TNF-alpha, infliximab, inhibits neutrophil chemotaxis and production of reactive oxygen species by blocking the priming effect of mononuclear cells on neutrophils. Immunopharmacol Immunotoxicol. 2005;27(2):187-98.

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  8. 7.Pay S, Erdem H, Pekel A, Simsek I, Musabak U, Sengul A, Dinc A Synovial Proinflammatory Cytokines and Their Correlation with Matrix Metalloproteinase-3 Expression in Behçet’s Disease. Does Interleukin-1 Play a Major Role in Behçet’s Synovitis? Rheumatol Int. 2006 May;26(7):608-13.

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  9. 8.Musabak U, Pay S, Erdem H, Simsek I, Pekel A, Dinc A, Sengul A. Serum Interleukin-18 Levels in Patients with Behçet’s Disease: Is Its Expression Associated with Disease Activity or Clinical Presentations? Rheumatol Int. 2006 Apr;26(6):545-50.

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  10. 9.Bozoglu E, Dinc A, Erdem H, Pay S, Simsek I, Kocar IH. Vascular endothelial growth factor and monocyte chemoattractant protein-1 in Behcet's patients with venous thrombosis. Clin Exp Rheumatol. 2005 Jul-Aug;23(4 Suppl 38):S42-8.

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  11. 10.Dinc A, Bayir A, Simsek I, Erdem H, Pay S, Turan M. The proportional Venn diagram of Behcet's disease-related manifestations among young adult men in Turkey. Clin Exp Rheumatol. 2005 Jul-Aug;23(4 Suppl 38):S86-90.

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  12. 11.Pay S, Turkcapar N, Kalyoncu M, Simsek I, Beyan E, Ertenli I, Ozturk MA, Duzgun N, Erdem H, Ozbalkan Z, Kiraz S, Kinikli G, Besbas N, Dinc A, Ates A, Olmez U, Calguneri M, Tiryaki Aydintug O, Bakkaloglu A, Turan M, Turgay M, Karaaslan Y, Topaloglu R, Duman M, Ozen S; Ankara Rheumatology Study Group. A multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritis. Clin Rheumatol. 2006 Sep; 25(5): 639-644.

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  13. 12.Erdem H, Dinc A, Pay S, Simsek I, Turan M. Peripheral insulin resistance in patients with Behcet's disease. J Eur Acad Dermatol Venereol. 2006 Apr;20(4):391-5.

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  14. 13.Pay S, Musabak U, Simsek I, Pekel A, Erdem H, Dinc A, Sengul A. Expression of CXCR-1 and CXCR-2 chemokine receptors on synovial neutrophils in inflammatory arthritides: Does persistent or increasing expression of CXCR-2 contribute to the chronic inflammation or erosive changes? Joint Bone Spine. 2006 Dec 73(6): 691-6.

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  15. 14.Pay S, Simsek I, Erdem H, Dinc A. Immunopathogenesis of Behçet’s Disease with Special Emphasize on the Possible Role of Antigen Presenting Cells. Rheumatology Int 2007 Mar; 27(5):417-424.

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  16. 15.Erdem H, Pay S, Musabak U, Simsek I, Dinc A, Pekel A, Sengul A. Synovial angiostatic non-ELR CXC chemokines in inflammatory arthritides: does CXCL4 designate chronicity of synovitis? Rheumatol Int. 2007 Aug;27(10):969-73.

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  17. 16.Simsek I, Pay S, Pekel A, Dinc A, Musabak U, Erdem H, Sengul A. Serum proinflammatory cytokines directing T helper 1 polarization in patients with familial Mediterranean fever. Rheumatol Int. 2007 Jul;27(9):807-11

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  18. 17.Simsek I, Erdem H, Pay S, Sobaci G, Dinc A. Optic neuritis occurring with anti-Tumor Necrosis Factor-{alpha} therapy. Ann Rheum Dis. 2007 Sep;66(9):1255-8.

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  19. 18.Pay S, Abbasov T, Erdem H, Musabak U, Simsek I, Pekel A, Akdogan A, Sengul A, Dinc A. Serum MMP-2 and MMP-9 in patients with Behçet's disease: do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation? Clin Exp Rheumatol. 2007 Jul-Aug;25(4 Suppl 45):S70-5.

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  20. 19.Pay S, Simsek I, Erdem H, Pekel A, Musabak U, Sengul A, Dinc A. Dendritic cell subsets and type I interferon system in Behçet's disease: does functional abnormality in plasmacytoid dendritic cells contribute to Th1 polarization? Clin Exp Rheumatol. 2007 Jul-Aug;25(4 Suppl 45):S34-40.

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  21. 20.Pay S, Musabak U, Simsek I, Erdem H, Pekel A, Sengul A, Dinc A. Synovial lymphoid neogenetic factors in Behçet's synovitis: do they play a role in self-limiting and subacute course of arthritis? Clin Exp Rheumatol. 2007 Jul-Aug;25(4 Suppl 45):S21-6.

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  22. 21.Simsek I, Meric C, Erdem H, Pay S, Kilic S, Dinc A. Accuracy of recall of the items included in disease activity forms of Behçet's disease: comparison of retrospective questionnaires with a daily telephone interview. Clin Rheumatol. 2008 Oct;27(10):1255-60. Epub 2008 Apr 30.

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  23. 22.Odabasi E, Turan M, Erdem H, Tekbas F. Does mud pack treatment have any chemical effect? A randomized controlled clinical study. J Altern Complement Med. 2008 Jun; 14(5):559-65.

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  24. 23.Cinar M, Dinc A, Simsek I, Erdem H, Koc B, Pay S, Tunca Y, Kilic S, Gul D. The rate and significance of Mediterranean fever gene mutations in patients with ankylosing spondylitis: a three-month, longitudinal clinical study. Rheumatol Int. 2008 Nov;29(1):37-42. Epub 2008 Jul 3.

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  25. 24.Karacayli U, Mumcu G, Simsek I, Pay S, Kose O, Erdem H, Direskeneli H, Gunaydin Y, Dinc A. The close association between dental and periodontal treatments and oral ulcer course in behcet's disease: a prospective clinical study. J Oral Pathol Med. 2009 May;38(5):410-5. Epub 2009 Mar 5.

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  26. 25.Cinar M, Dinc A, Simsek I, Erdem H, Koc B, Pay S, Kilic S. Evaluation of the short-term efficacy of NSAIDs on patients with active ankylosing spondylitis in daily practice: a 3-month, longitudinal, observational study.Rheumatol Int. 2010 Jan;30(3):331-40. Epub 2009 May 23. Erratum in: Rheumatol Int. 2010 Jun;30(8):1141.

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  27. 26.Pay S, Pekel A, Simsek I, Musabak U, Erdem H, Dinc A, Kose O. Pronounced interferon-alpha production from plasmacytoid dendritic cells in patients with Behçet's disease following CpG D ODN stimulation. Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S37-42.

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  28. 27.Keskin F, Pay S, Musabak U, Sagkan RI, Erdem H, Simsek I, Kose O, Dinc A, Sengul A. IL-18 promoter polymorphisms confer susceptibility to Behçet's disease, particularly to the mucocutaneous form, in a Turkish population. Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S108-9.

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  29. 28.Pay S, Musabak U, Cobankara V, Sagkan RI, Simsek I, Keskin F, Erdem H, Kose O, Dinc A. IFNAR1 and IFNAR2 polymorphisms in patients with Behçet's disease. Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S110-1.

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  30. 29.Simsek I, Koz C, Basar N, Sari I, Erdem H, Pay S, Kisacik B, Bahce M, Dinc A. Mediterranean fever (MEFV) gene mutation frequency is not increased in adults with rheumatic heart disease. Clin Rheumatol. 2011 Apr;30(4):491-5. Epub 2010 Jul 20.

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  31. 30.Kisacik B, Oren C, Kasifoglu T, Yilmaz S, Yilmaz O, Simsek I, Erdem H, Pay S, Saglam M, Dinc A. Investigation of the veins in patients with Behçet's disease with no known vascular event by Doppler ultrasonograpy. Rheumatol Int. 2012 Feb;32(2):303-6

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  32. 31.Yilmaz O, Yilmaz S, Kisacik B, Aydogdu M, Bozkurt Y, Erdem H, Pay S, Saglam M, Dinc A. Varicocele and epididymitis in Behcet disease. J Ultrasound Med. 2011 Jul;30(7):909-13

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  33. 32.Cinar FI, Unver V, Yilmaz S, Cinar M, Yilmaz F, Simsek I, Erdem H, Pay S, Dinc A. Living with scleroderma: patients' perspectives, a phenomenological study. Rheumatol Int. 2012 Nov;32(11):3573-9.

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  34. 33.Karadag O, Tufan A, Yazisiz V, Ureten K, Yilmaz S, Cinar M, Akdogan A, Erdem H, Ozturk MA, Pay S, Dinc A. The factors considered as trigger for the attacks in patients with familial Mediterranean fever. Rheumatol Int. 2013 Apr;33(4):893-7.

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  35. 34.Gok M, Erdem H, Gogus F, Yilmaz S, Karadag O, Simsek I, Sagkan RI, Saglam M, Musabak U, Dinc A, Pay S. Relationship of ultrasonographic findings with synovial angiogenesis modulators in different forms of knee arthritides. Rheumatol Int. 2013 Apr;33(4):879-85.

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  36. 35.ii)Sanal HT, Yilmaz S, Kalyoncu U, Cinar M, Simsek I, Erdem H, Pay S, Dinc A, Tayfun C. Value of DWI in visual assessment of activity of sacroiliitis in longstanding ankylosing spondylitis patients. Skeletal Radiol. 2013 Feb;42(2):289-93.

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  37. 36.Sanal HT, Yilmaz S, Simsek I, Cinar M, Erdem H, Pay S, Dinc A, Tayfun C. Apparent diffusion coefficients of sacroiliitis in patients with established ankylosing spondylitis. Clin Imaging. 2013 Jul-Aug;37(4):734-9.

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  38. 37.Cinar M, Akar H, Yilmaz S, Simsek I, Karkucak M, Sagkan RI, Pekel A, Erdem H, Avci IY, Acikel C, Musabak U, Tunca Y, Pay S. A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population. Rheumatol Int. 2013 Nov;33(11):2851-8.

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  39. 38.Yilmaz S, Cinar M, Pekel A, Simsek I, Musabak U, Erdem H, Pay S. The expression of transmembrane and soluble CXCL16 and the relation with interferon-alpha secretion in patients with Behçet's disease. Clin Exp Rheumatol. 2013 May-Jun;31(3 Suppl 77):84-7.

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  40. 39.Yilmaz S, Simsek I, Cinar M, Erdem H, Kose O, Yazici Y, Pay S. Patient-driven assessment of disease activity in Behçet's syndrome: cross-cultural adaptation, reliability and validity of the Turkish version of the Behçet's Syndrome Activity Score. Clin Exp Rheumatol. 2013 May-Jun;31(3 Suppl 77):77-83.

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  41. 40.F.I.Cinar, V.Unver, M.Cinar, S.Yilmaz, I.Simsek, N.Tosun, H.Erdem, F.Yilmaz, S.Pay, A.Dinc. Coping Strategies for Activities of Daily Living in Women Whose Hands Affected by Systemic Sclerosis. Journal of Clinical Nursing, Doi:10.1111/jocn.12283.

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  42. 41.Yilmaz S, Karadag O, Yazisiz V, Altun B, Gezer M, Karaman M, Cinar M, Erdem H, Pay S, Dinc A. Systemic involvements and preferred treatments in a large cohort of Behçet's disease. Rheumatol Int. 2013 Dec;33(12):3025-30.

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  43. 42.Mas MR, Saglamkaya U, Kubar A, Colakoglu M, Ateskan U, Erdem H, Nalbant S, Eyileten T, Cömert B, Unal T, Kocabalkan F. Hepatitis G Virus İnfection Among Patients Undergoing Hemodialysis. Nephron, 80, 247-248,1998.

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  44. 43.Mas MR, Simsek I, Can C, Ateskan U, Erdem H, Kocabalkan F. Fulminant Hepatic Failure As The Initial Manifestation of Primary Hepatocellular Carcinoma. European Journal of Gastroenterology and Hepatology, 12, 1-4, 2000.

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  45. 44.Dinc A, Soy M, Pay S, Simsek I, Erdem H, Sobacı G. A Case of Churg-Strauss Syndrome presenting with cortical blindness. Clinical Rheumatology 19: 318-320, 2000.

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  46. 45.Pay S, Dinc A, Simsek I, Erdem H, Soy M. Sulphasalazine induced angioimmunoblastic lymphadenopathy. Rheumatology International 20: 25-27, 2000.

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  47. 46.Dinc A, Erdem H, Rowczenio D, Simsek I, Pay S, Bahce M, Lachmann H. Autosomal dominant periodic fever with AA amyloidosis: tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a Turkish family. J Nephrol. 2005 Sep-Oct;18(5):626-9.

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  48. 47.Erdem H, Baylan O, Simsek I, Dinc A, Pay S, Kocaoglu M. Delayed diagnosis of tuberculous arthritis. Jpn J Infect Dis. 2005 Dec;58(6):373-5.

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  49. 48.Erdem H, Simsek I, Pay S, Dinc A, Deniz O, Ozcan A. Diffuse pulmonary amyloidosis that mimics interstitial lung disease in a patient with familial Mediterranean fever. J Clin Rheumatol. 2006 Feb;12(1):34-6.

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  50. 49.Erdem H, Dinc A, Pay S, Simsek I, Uysal Y. A neuro-Behcet's case complicated with intracranial hypertension successfully treated by a lumboperitoneal shunt. Joint Bone Spine. 2006 Mar; 73(2): 200-1.

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